MASS SPECTROMETRY IMAGING (MSI)
Mass spectrometry imaging (MSI) is a cutting-edge technique used to analyze the spatial distribution of molecules in biological and material samples. By measuring the molecular masses of biomarkers, peptides, and proteins, MSI allows for a completely untargeted approach to visualizing tissues. Multiple analytes, including drugs, metabolites, proteins, and lipids, can be recorded in parallel on tissue, providing a comprehensive view of the molecular composition of the sample. MSI has high potential for identifying unknown components involved in biological interactions and compartmentalized biological changes. Training and expertise for sample preparation up to the imaging process are available.
Application
– Small molecule distributions
– Bio- and polymeranalytics
– Peptides / lipids in cells
– Nanoparticles (Viruses, Polymers)
Image | Svirkova et al. 2018; Analyst, 2018, 143, 2587-2595